The book I'm working through covers (on its way to the Artin-Wedderburn theorem) the Jacobson Density theorem:
Let $L$ be an irreducible left $R$-module, with $D := \text{End}_{R-}(L)^{\text{op}}$ (so $L$ is a $(R,D)$-bimodule).
Let $v_1,\dots,v_n \in L$ be elements that are linearly independent over $D$.
Then for any set $w_1,\dots,w_n \in L$, there exists $r \in R$ such that $rv_i = w_i$ for each $i$.
It has the following corollary:
Under the above assumptions, note that $L$ is a right $D$-vectorspace (since $D$ is a division ring by Schur's Lemma).
Then if $L$ is finite-dimensional over $D$, the associated representation $\lambda: R \to \text{End}_{-D}(L)$ is surjective.
(This just follows by picking a (finite) basis of $L$ over $D$, let $f \in \text{End}_{-D}(L)$, and seeing where $f$ sends the basis elements; then JDT says $f$ acts on the basis as multiplication by some $r$.)
We also have Burnside's Theorem as a corollary: when $R$ is an algebra over algebraically-closed $\mathbb{k}$, by Schur's Lemma we have $\text{End}_{R-}(L)^{\text{op}} \cong \mathbb{k}$ for finite-dimensional $L$; and so we get the statement $\lambda: R \to \text{End}_{\mathbb{k}}(L)$ is surjective.
The question, then: what's a counterexample to this in the non-finite-dimensional case? That is, what, if any, is an example of a ring $R$ and irreducible $R$-module $L$, with $D := \text{End}_{R-}(L)^{\text{op}}$, where the associated representation $R \to \text{End}_{-D}(L)$ is not surjective?
Per JDT, necessarily $L$ must be infinite-dimensional over $D$. Bonus points if $R$ is an algebra over an algebraically-closed field, so as to relate to Burnside's theorem specifically, but I'd be happy with any example.
For the sake of showing I made an effort: frankly, I think my main obstacle is not knowing good examples of infinitely-generated irreducible modules. Also, I saw this question, which is almost what I was looking for, but the example the sole answer gives is a semisimple module, not simple.
I started with $\mathbb{C}[x]$-modules, but eventually realized that, since isomorphism classes of irreducible modules are in bijection with maximal ideals, and the only maximal ideals of $\mathbb{C}[x]$ are of the form $(x - a)$ for $a \in \mathbb{C}$, we get not just finite-dimensional but in fact one-dimensional irreducibles (corresponding to 1x1 Jordan blocks); and, in fact, the nullstallensatz says (if I'm thinking of this correctly?) that the only maximal ideals of $\mathbb{C}[x_1,\dots,x_n]$ are of the form $(x_1 - a_1,\dots,x_n - a_n)$ with, again, a one-dimensional quotient.
The natural next place to go would be $\mathbb{C}[x_1,x_2,x_3,\dots]$ in countable variables, but I'm not really sure what maximal ideals "look like" here. Other answers on this site suggest I can get non-nullstallensatz-like maximal ideals in uncountable-many variables via something like $R := \mathbb{C}[\{X_i\}_{i \in \mathbb{C}(t)}] \to \mathbb{C}(t)$, $X_i \mapsto i$, which is surjective onto a field and so has maximal kernel; but then it seems to me that, since $R$ just acts by multiplying and then quotient'ing, $D := \text{End}_{R}(\mathbb{C}(t))$ should (I think?) be the same as $\text{End}_{\mathbb{C}(t)}(\mathbb{C}(t)) \cong \mathbb{C}(t)$, and then $\lambda: R \to \text{End}_{-D}(\mathbb{C}(t)) \cong \mathbb{C}(t)$ is, in fact, surjective; if I did that right, then a similar issue should occur with any other field extensions.
I tried finding some other infinite-dimensional irreducible modules -- Wikipedia suggests some Lie algebra stuff? But unfortunately I don't know anything about representations of Lie algebras. There's also my professor's perennial "weird" module example, the Weyl algebra's action by x and d/dx on $\mathbb{C}[x]$, but I did my best to work through the calculations there and I think I found that the endomorphisms of $\mathbb{C}[x]$, as a subring of $\text{End}_{\mathbb{C}}(\mathbb{C}[x])$ -- which is the column-finite countably-indexed matrices $\mathbb{C}^{\mathbb{N} \times \mathbb{N}}$ -- that commute with the matrices $X$ and $Y$ corresponding to x and d/dx... are only multiples of the identity, ie $\text{End}_{A_1}(\mathbb{C}[x]) \cong \mathbb{C}$; and another answer on this site suggests the only nontrivial ideal of $\mathbb{C}^{\mathbb{N} \times \mathbb{N}}$ is the set of finite-rank maps, whereas both $X$ and $Y$ are infinite-rank, meaning the representation map $A_1 \to \text{End}_{\mathbb{C}}(\mathbb{C}[x]) \cong \mathbb{C}^{\mathbb{N} \times \mathbb{N}}$ is surjective. So... I'm stuck. (Sidenote: I'd also welcome comments that any of my analyses in the above paragraphs are incorrect in some way.)