Let $f_1,f_2:[0,1]\to S^3$, $g:M\to S^3$ and $h:\mathbb{R}P^2\to S^3$ be inyective maps, where $M$ is the Möbius strip. Assume that $\mathrm{Im}f_1\cap \mathrm{Im}f_2=\emptyset$.
I want to compute $H_*(S^3- \mathrm{Im}f_1\cup \mathrm{Im}f_2)$, $H_*(S^3-\mathrm{Im}g)$ and $H_*(S^3-\mathrm{Im}h)$.
Sice all maps are injective and continuous between compact Hausdorff spaces, they are homeomorphisms onto their images. My idea is to compute these homologies using excision surrounding each image by an open ball, and then using Mayer-Vietoris.
In order to use Mayer-Vietoris I'd like to be able to say that $H_*(S^3-A)=H_*(S_3-B)$ whenever $A$ and $B$ are homeomorphic proper closed subsets, or at least $H_*(\mathbb{R}^3-A)=H_*(\mathbb{R}^3-B)$ (and therefore I would use the excision part before). That's because I would be able to easily decompose the spaces, for example, I could choose any obvious embedding of the unit interval.
From Madsen's From Calculus To Cohomology (theorem 7.2) I know that $H^p(\mathbb{R}^n-A)=H^p(\mathbb{R}^n-B)$ for the deRham Cohomology. I would like to mimic the proof, but it uses the fact that the the deRham cohomology has coefficients on the field $\mathbb{R}$, namely, he says that
$H^0(\mathbb{R}^n-A)/\mathbb{R}\cong H^0(\mathbb{R}^n-B)/\mathbb{R}$
implies $H^0(\mathbb{R}^n-A)=H^0(\mathbb{R}^n-B)$, which is not always true for $\mathbb{Z}$ coefficients, since one of the groups could have non-trivial torsion subgroup. In addition, it is a statement about cohomology, not about homology, though I think that's not essential in the proof.
So my question is
Is any of the isomorphisms $H_*(S^3-A)\cong H_*(S^3-B)$ or $H_*(\mathbb{R}^3-A)\cong H_*(\mathbb{R}^3-B)$ true? If not, how can I approach this problem?