This, too, is a partial answer. I originally wrote it to argue that GEdgar's suggestion of $C(\beta\mathbb{N})$ and similar are not counterexamples (i.e., your hypothetical equivalence holds for them), but flubbed a key point. Nevertheless, my argument shows (in rather elementary fashion) that a counterexample should have to be rather exotic.
Specifically, let $K$ be any infinite compact Hausdorff space — say, $\beta\mathbb{N}$, $[0,1]^{\mathbb{R}}$, or just $\omega_1+1$ with the ordinal topology. I will show that if $K$ admits a nontrivial convergent sequence in the sense of this paper — that is, a convergent sequence that is not eventually constant — then $K$ cannot be a counterexample. Not all infinite compact Hausdorff spaces admit such a sequence because they need not be sequentially compact; in particular, such is the case for $\beta\mathbb{N}$.
Anyways, on to the proof!
Pick a maximal set $S$ of mutually singular measures on the Borel $\sigma$-algebra associated with the topology on $K$; $S$ always exists by Zorn's Lemma. Endow $S$ with the discrete topology and place the Borel $\sigma$-algebra on $S\times K$; the latter has a natural measure, given by $$\lambda(A)=\sum_{s\in S}{s(\{x:(s,x)\in A\})}$$
Now, $C(K)^*$ is the space of Borel-regular measures on $K$. By Lebesgue decomposition and Radon-Nikodym, $T:C(K)^*\to L^1(S\times K)$; $$T(\mu)(s,x)=\frac{d\mu}{ds}(x)$$ (where the Radon-Nikodym derivative vanishes if $\mu\perp s$) is an isometric isomorphism. Correspondingly $C(K)^{**}\cong L^{\infty}(S\times K)$, and I now unabashedly identify across both isomorphisms.
In particular, pick any sequence $\{\mu_n\}_{n=0}^{\infty}\in L^1(S\times K)^{\omega_0}$. $\{\mu_n\}_n\overset{*}{\rightharpoonup}0$ iff, for all $f\in C(K)$, we have $$\lim_{n\to\infty}{\iint_{S\times K}{f(x)\mu_n(s,x)\,d^2(s,x)}}=0$$ and $\{\mu_n\}_n\rightharpoonup0$ iff, for all $f\in L^{\infty}(S\times K)$, we have $$\lim_{n\to\infty}{\iint_{S\times K}{f(s,x)\mu_n(s,x)\,d^2(s,x)}}=0$$
With those preliminaries in hand, an easy construction now shows that the topologies of weak and weak-$*$ convergence do not coincide on sequences in $C(K)^*$. Choose any sequence $\{q_n\}_{n=0}^{\infty}\in K^{\omega_0}$ of distinct elements, tending to a limit $q_{\infty}$. W/oLoG, for each $n$, the Dirac mass $\delta_{q_n}\in S$. So let $$\mu_n(s,x)=\begin{cases}
1 & s=\delta_{q_{2n}} \\
-1 & s=\delta_{q_{2n+1}} \\
0 & \text{otherwise}
\end{cases}$$ Then, since any $f\in C(K)$ is continuous at $q_{\infty}$, we can compute $$\iint_{S\times K}{f(x)\mu_n(s,x)\,d^2(s,x)}=f(q_{2n})-f(q_{2n+1})\to0$$ as $n\to\infty$. But just as clearly the pointwise sum $\sum_n{\mu_n}\in L^{\infty}(S\times K)$, so that $$\iint_{S\times K}{\left(\sum_n{\mu_n}\right)(s,x)\mu_n(s,x)\,d^2(s,x)}=2\not\to0$$ as $n\to\infty$.
https://en.wikipedia.org/wiki/Eberlein–Šmulian_theorem? – GEdgar Jun 20 '22 at 15:42