Suppose you have an expression of the form $$\frac{n!}{k_1! k_2! \cdots k_r!}$$ where $\displaystyle \sum k_i \le n$. The expression must be an integer, because it's the number of permutations of $n$ objects where the $k_i$ are the number of repeated objects. For example, there are $\frac{11!}{4!4!2!}$ ways to order the letters in the word MISSISSIPPI.
The question is, can every integer in the denominator be canceled with some single integer in the numerator (i.e. every integer in the denominator should divide some integer in the numerator), or is it possible that in order to cancel some integer in the denominator you might have to combine (multiply) some number of integers in the numerator? For example, is it possible for an expression in the above form to look something like $\frac{2 \cdot 2 \cdot 3 \cdot 3}{4 \cdot 9}$ in which case you would not be able to cancel the 4 or the 9 in the denominator with any single integer in the numerator, but you could if you first multiplied the two 2s and two 3s in the numerator.
I cannot find a counterexample but I also cannot prove that it is always possible.