I posted this question on mathoverflow, and there I got a comment by
Fedor Petrov that there is no way to find the needed constant $0 < C < 1$ even if all degrees are equal to $(n-1)/2$.
Here is a detailed explanation on why is that.
If a graph has $2k-1$ vertices, and is $k$-regular, it has to be connected. In our case the degree $(n-1)/2$ is a bit smalle than half of the vertice, relative part of diconnected graphs on $n$ vertices with degree $(n-1)/2$ goes to zero as $n$ goes to infinity, as each vertex gets closer to be connected to half of the vertices of the graph.
Now, let's compute the bound on the number of $(n−1)/2$-regular graphs. In this paper the number of $d$-regular graphs on $n$ vertices is asymptotically equal to
$$\frac{\binom{n-1}{d}^n \binom{\binom{n}{2}}{m}}{\binom{n(n-1)}{2m}}\cdot e^{\frac{1}{4}},$$
where $m = dn/2$.
Applying $d = (n-1)/2$ we get
$$\frac{\binom{n-1}{(n-1)/2}^n \binom{\binom{n}{2}}{\frac{1}{2}\binom{n}{2}}}{\binom{2\binom{n}{2}}{\binom{n}{2}}}e^{\frac{1}{4}}.$$
Applying the Stirling's approximation to central binomial coefficient we get
$$\binom{2N}{N} \approx \frac{2^{2N}}{\sqrt{\pi N}}.$$
Thus,
$$\frac{\binom{n-1}{(n-1)/2}^n \binom{\binom{n}{2}}{\frac{1}{2}\binom{n}{2}}}{\binom{2\binom{n}{2}}{\binom{n}{2}}} = \frac{ \frac{2^{n(n-1)}}{\pi^{n/2} (n-1)^{n/2}} \frac{2^{\frac{n(n-1)}{2}}}{\sqrt{\pi \frac{n(n-1)}{4}}}}{ \frac{2^{2\frac{n(n-1)}{2}}}{\sqrt{\pi \frac{n(n-1)}{2}}}}e^{\frac{1}{4}} = e^{\frac{1}{4}} \cdot 2^{\frac{1}{2}} 2^{\frac{n(n-1)}{2} - \frac{n\log(n-1)}{2} - \frac{n\log(\pi)}{2}},$$
and it is eacy to check that for any $C < 1$ for any sufficiently large $n$ it holds that
$$ \frac{n(n-1)}{2} - \frac{n\log(n-1)}{2} - \frac{n\log(\pi)}{2} = \frac{n}{2}(n - \log\pi(n-1))> C \frac{n(n-1)}{2}.$$