There is a super-pretty, and very poweful, theorem which you can use here. Its proof is not so hard (probably master's level). Reference is: Baumslag, Benjamin; Pride, Stephen J. Groups with two more generators than relators. J. London Math. Soc. (2) 17 (1978), no.3, 425–426.
Theorem (B.Baumslag-Pride).
If $G$ admits a presentation with $2$ more generators than relators, then $G$ contains a finite index subgroup which surjects onto the free group of rank $2$, $F_2$.
In modern parlance, $G$ is large.
To apply this to your problem, note that by considering abelianisations of one-relator groups, if $\mathbb{Z}^3$ is an $n$-generator one-relator group then $n\geq3$. As $3-1\geq2$, the Baumslag-Pride theorem then says that $\mathbb{Z}^3$ contains a finite index subgroup $H$ which surjects onto $F_2$. As $H$ is necessarily abelian but $F_2$ is not, we have a contradiction. Hence, $\mathbb{Z}^3$ is not a one-relator group.
In fact, using more powerful tools we can prove the following.
Theorem.
The only possible abelian subgroups of a one-relator group are cyclic groups and $\mathbb{Z}^2$.
One way to prove this would be to first use (virtual) cohomological dimension to eliminate the possibility of $\mathbb{Z}^n$ for $n\geq3$ - one relator groups have $(v)cd\leq2$, and hence so do all their subgroups, while $cd(\mathbb{Z}^n)>2$. [This argument also works for the problem in the question.]
We therefore just need to eliminate $\mathbb{Z}\times\mathbb{Z}_n$ and $\mathbb{Z}_m\times\mathbb{Z}_n$ as possibilities. To do this, first apply a theorem of Pride (Pride, Stephen J. The two-generator subgroups of one-relator groups with torsion. Trans. Amer. Math. Soc.234(1977), no.2, 483–496) which says that if a subgroup of a one-relator group is two-generated and contains elements of finite order, then the subgroup is itself a one-relator group, and moreover (via another deep result...) the relator is a proper power. So then:
- $\mathbb{Z}_m\times\mathbb{Z}_n$ is eliminated by considering abelianisations.
- For $\mathbb{Z}\times\mathbb{Z}_n$, we can apply a beefed-up version of the Baumslag-Pride result, due to Gromov, which states that if $G$ admits a presentation with one more generator than relator and where at least one relator is a proper power, then $G$ contains a finite index subgroup which surjects onto $F_2$. If $\mathbb{Z}\times\mathbb{Z}_n$ is a subgroup of a one-relator groups, then as noted above it a one-relator group where the relator is a proper power. It is also non-cyclic, and so Gromov's result applies to this one-relator presentation. However, no subgroup of $\mathbb{Z}\times\mathbb{Z}_n$ surjects onto $F_2$.
Phew.