The following assertion was made while discussing a question regarding Alexandrov spaces in topology.
Every countably infinite preorder has exactly continuum many endomorphisms.
Here, a preordered set is a set $P$ together with a relation $\le$ that is reflexive and transitive. Preordered sets form a category where the morphisms between two preorders are the monotone functions (satisfying $x\le y\implies f(x)\le f(y)$).
So assume $P$ is countably infinite. The question asks the number of monotone maps from $P$ to itself, which should be $2^{\aleph_0}$. (It cannot be more than that, since that is the number of set functions from $P$ to itself.)
Below is a partial proof. How can the last step be completed?
Step 1: Given the preorder, there is an associated equivalence relation defined by $x\sim y$ if $x\le y$ and $y\le x$. If one of the equivalence classes, say $A$, is infinite, any map that sends $A$ to itself and fixes elements not in $A$ is monotone, and there are continuum many such maps. Otherwise, every equivalence class is finite. So the quotient structure $P/\sim$, which is a poset when given the natural induced order relation, is infinite and every monotone self-map of $P/\sim$ lifts to at least one monotone self-map of $P$. So without loss of generality we can assume $P$ is a poset.
Step 2: If the order relation on $P$ is the identity relation (= elements are only comparable to themselves), then any map from $P$ to itself is monotone, and there are countinuum many such maps. So we can assume there are at least two distinct comparable elements, say $x_0\le x_1$.
Step 3: Suppose $P$ has an infinite antichain $D$ (= no two elements are comparable). Any subset $A\subseteq D$ gives rise to an upper set $A^{\uparrow}=\{x\in P:x\ge a \text{ for some } a\in A\}$, and this upper set uniquely determines $A$ as its set of minimal elements. So there are continuum many upper sets $U$ in $P$. For each such $U$, the map sending $U$ to $x_1$ and the complement of $U$ to $x_0$ is monotone. So we have countinuum many such maps. We can now assume $P$ has no infinite antichain.
Step 4: As shown for example here, $P$ must then contain an infinite chain (= all elements comparable).
Step 5: handle the case of an infinite chain ...
(Added later) From the comment to the answer, we also conclude:
Every infinite preorder has at least continuum many endomorphisms.