Are there infinitely many primes $p<q$, $p,q\neq 2,3$ such that $pq=a^2+b^4$ where $a,b\in \mathbb{Z}$ ? I've no idea if this is a very easy or very hard question. Any known result about this ? Thank you for your comments !
EDIT : using mod $4$ arguments you can derive very easily conditions on $a$ and $b$. Also using Gaussian integers, this product $pq$ boils down to the product of $4$ gaussian irreducible elements. Note that $p,q$ must be congruent to $1$ mod $4$.