The group algebra $k[G]$ of a finite group $G$ over a field $k$ knows little about $G$ most of the time; if $k$ has characteristic prime to $|G|$ and contains every $|G|^{th}$ root of unity, then $k[G]$ is a direct sum of matrix algebras, one for each irreducible representation of $G$ over $k$, so $k[G]$ only knows the dimensions of the irreducible representations of $G$.
The group ring $\mathbb{Z}[G]$, on the other hand, knows at least as much as $k[G]$ for every $k$ (which one can obtain by tensoring with $k$); this information should let you deduce something about the entries in the character table of $G$, although I'm not sure exactly what. If the characteristic of $k$ divides $|G|$ then $k[G]$ knows something about the modular representation theory of $G$, although again, I'm not sure exactly what. So:
How strong of an invariant is $\mathbb{Z}[G]$? More precisely, what group-theoretic properties of $G$ do I know if I know $\mathbb{Z}[G]$? What are examples of finite groups $G_1, G_2$ which are not isomorphic but which satisfy $\mathbb{Z}[G_1] \cong \mathbb{Z}[G_2]$?
If in addition to $\mathbb{Z}[G]$ we are given the augmentation homomorphism $\mathbb{Z}[G] \to \mathbb{Z}$ then it looks like we can recover the group cohomology and homology of $G$, so it seems plausible that $\mathbb{Z}[G]$ contains quite a lot of information.
At a minimum, setting $k = \mathbb{R}$ I think we can compute the Frobenius-Schur indicator of every complex irreducible representation of $G$.
Edit: It seems the second problem is known as the isomorphism problem for integral group rings and is quite hard.