Another approach specific to symmetric tridiagonal matrices is to use the following recurrence. Let $a_i$ be the entries of the main diagonal, and let $b_j$ be the entries of the off-diagonal. Then the determinant is given by $$ \begin{align*} d_{-1} &= 0 \\ d_0 &= 1 \\ d_n &= a_n d_{n-1} - b_{n-1}^2 d_{n-2} \end{align*} $$ This gives the series of determinants of its leading principal minors. In your case, this is: $$\begin{align*}
d_1 = 4\cdot 1 - 0^2 \cdot 0 = 4 \\
d_2 = 5\cdot 4 - 2^2 \cdot 1 = 16 \\
d_3 = 5\cdot 16 - 2^2 \cdot 4 = 64 \\
d_4 = 5\cdot 64 - 2^2 \cdot 16 = 256 \\
d_5 = 5\cdot 256- 2^2 \cdot 64 = 1024 \\
\end{align*}$$
Since they're all positive, Sylvester's criterion shows that the matrix is positive-definite.
Since you asked for a "fast" way, I'll note that this takes linear time to execute on a computer. I'll also note that a faster way of doing this on paper (fewer operations) is to divide the recurrence by the previous term to get $s_n = a_n - b^2_{n-1} / s_{n-1}$ with $s_0=1$ and $b_0=0$. If $a_1$ is positive and $s_n$ remains positive throughout, then the recurrence never changes sign, so $d_n$ is positive as before.