The curve-to-projective extension theorem says:
If $C$ is a pure dimension 1 Noetherian scheme over an affine base $S$, and $p \in C$ is a regular closed point of it. Suppose $Y$ is a projective $S$-scheme. Then any morphism $C \setminus \{p\} \to Y$ extends to all of $C$.
This is 16.5.1 in Vakil's notes. Then he argues that this extension is unique in two ways: one is to replace $C$ by an open neighborhood of $p$ that is reduced, and the other is to note that maps to separated schemes can be extended over an effective Cartier divisor in at most one way.
For the argument to go through we need the fact that $\mathscr{O}_{C,p}$ is reduced, or that $p$ is cut out by a non-zero-divisor. Why is that true?