Assume we have a measurable space $(X, \mathscr{B})$, where $X$ is a separable metric space and $\mathscr{B}$ is the Borel sigma algebra. Then, since $X$ is separable, then, $\mathscr{B}$ equals to the sigma algebra generated by open balls.
The question: assume that two probability measures on $\mathscr{B}$ are such that they agree on every open ball (just ball!) of $X$. Is it true that they are equal?