Yes.
To make your question more precise, you ask if whenever $F\subseteq K$ is a field extension and $f\in F[X]$ is irreducible over $F$, with root $\alpha\in K$, do we have that $F(\alpha)\cong F[X]/f$.
Consider $\phi\colon F[X]\to F[\alpha]$ defined as identity on $F$ and $X\mapsto \alpha$. This is a well-defined homomorphism, and you can check that its kernel is precisely $(f)$. Indeed, if for $g\in F[X]$ we have that $\phi(g)=0$, it means that by definition $g(\alpha)=0$. But then, since $f$ is the minimal polynomial of $\alpha$ (because $\alpha$ is its root and it is irreducible), you must have that $f$ divides $g$, whence $g\in (f)$. Conversely, if $g\in (f)$, clearly $\varphi(g)=f(\alpha)\cdot h(\alpha)=0$.
By the preceding paragraph, $\phi$ induces an isomorphism $\bar\phi\colon F[X]/(f)\to F[\alpha]$ (it is clearly onto!). Since you know that $F[X]/(f)$ is a field, $F[\alpha]$ is also a field, so $F[\alpha]=F(\alpha)$ and we are done.