Let $M$ be a topological manifold, and consider $N\subset M$ with the subspace topology.
Assume $N$ is a topological manifold of codimension $0$. Must it be open in $M$?
It is clearly the case for any locally flat submanifold. But does it hold in general? (See discussion on possibilities of defining submanifolds).
(I know this holds in the smooth case, but there we have the inverse function theorem, so we get a local diffeomorphism).