Let $Z$ be the matrix of $M_n(F)$ such that $Z$ contains only the zero of $F$ everywhere.
Let $E_{i,j}$ be the matrix of $M_n(F)$ such that $E_{i,j}$ contains only the identity of $F$ in $(i,j)$ and the zero of $F$ everywhere else.
We are looking for $D : M_n(F) \rightarrow M_n(F)$ such that
\begin{align}
D(A+B)=&\;D(A)+D(B) & (1)\\
D(AB)=&\;AD(B)+D(A)B & (2)
\end{align}
- Show that $D(Z)=Z$ (using $(2)$).
- Show that $\forall i\; D(E_{i,i})=Z$ (using $(2)$ and $E_{i,i}=E_{i,i}.E_{i,i}$ and $Z=E_{i,i}.E_{j,j}$ for $i\neq j$).
- Show that $\forall i,j\;D(E_{i,j})=c_{i,j}.E_{i,j}$, for some $c_{i,j}\in F$ (using $(2)$ and $E_{i,j}=E_{i,i}.E_{i,j}=E_{i,j}.E_{j,j}$).
- Show that $\forall i,j,k\; c_{i,j}+c_{j,k}=c_{i,k}$ (using $(2)$ and $E_{i,k}=E_{i,j}.E_{j,k}$).
- Show that $D$ is entirely defined by $c_{i,i+1}$ (and (1)), and such a $D$ is indeed a differentiation (using (1), (2) and previous results).