The internet is full of algorithms to calculate the modulo operation of large numbers that have the form $a^e \bmod p$. How about numbers with unknown factorization. More precisely, let's say I have a 4-byte sized modulus prime $p$, and a large number $a$ stored in memory as an array of bytes, that is, $a = [a_{k-1}, a_{k-2},\dots, a_0]$, where $ k \gg 4$.
How to calculate the modulo operation $a \bmod p$ efficiently? Please, cite a reference for your algorithm if it is possible.
The map from natural numbers to the ring of remainders is a homomorphism, which is a way to say that it has all sorts of nice properties with respect to operations + and *. In particular, a+b has the same remainder as mod_p(a) + mod_p(b) and a*b, the same as mod_p(a)*mod_p(b).
So, mod_p(a_0 + a_1*2^8 + a_2*2^16 + ...) = mod_p(mod_p(a_0) + mod_p(a_1)*mod_p(2^8) + mod_p(a_2)*mod_p(2^16) + ...).
The modulo operation is one of the basic arithmetic operations. As such, you can use the division algorithm you learned in school (if they still teach it) to calculate $a \bmod p$, which is the remainder in the division of $a$ by $p$. Efficient implementations are also available in libraries like GMP.