We will prove that for any integer $n \geq 1$, the number $n! + 1$ is not divisible by any integer $k$ such that $2 \leq k \leq n$.
Proof (by contradiction):
Assume (for the sake of contradiction) that there exists an integer $k$ with $2 \leq k \leq n$ such that $k \mid (n! + 1)$.
But since $k \leq n$, it follows that $k$ is one of the factors of $n!$. So $k \mid n!$, which means $n! \equiv 0 \pmod{k}$.
Then, $n! + 1 \equiv 0 + 1 \equiv 1 \pmod{k}$, which implies $k \nmid (n! + 1)$.
This contradicts our assumption that $k \mid (n! + 1)$.
Therefore, our assumption must be false. So no integer $k$ with $2 \leq k \leq n$ divides $n! + 1$.
$\mathbb{QED}$
Note: if asked to prove by contradiction, just assume the opposite of what is given and try to work your way through it.