We assume $\alpha_j\in \mathbb{R}$ and $x_j>0$ for $j=1,2,\ldots, n.$ The proof will go by induction on $n.$ The conclusion is obviously true for $n=1.$ Assume the conclusion is true for $n-1.$ Assume $\det A=0.$ Equvalently the columns of $A$ are linearly dependent. Therefore there exist constants $c_1,c_2,\ldots , c_n$ not all equal $0,$ such that
the function
$$c_1x^{\alpha_1}+c_2x^{\alpha_2}+\ldots +c_nx^{\alpha_n}$$ vanishes at the points $0<x_1<x_2<\ldots < x_n.$ Hence the function
$$f(x)=c_1+c_2x^{\alpha_2-\alpha_1}+\ldots +c_nx^{\alpha_n-\alpha_1} \tag{*}$$
vanishes at $0<x_1<x_2<\ldots < x_n$ with $\alpha_i-\alpha_1>0, \forall i>1$ and strictly increasing, satisfying the induction hypothesis. By the Rolle theorem function
$$f'(x)=c_2(\alpha_2-\alpha_1)x^{\alpha_2-\alpha_1-1}+\ldots +c_n(\alpha_n-\alpha_1)x^{\alpha_n-\alpha_1-1}$$
vanishes at $\{u_1,u_2,\ldots,u_{n-1}\}$ where $(x_i)_{i=1}^n$ and $(u_i)_{i=1}^{n-1}$ interlace, i.e. $0<x_1<u_1<x_2<u_2<\ldots<x_{n-1}<u_{n-1}<x_n$.
By induction hypothesis we conclude that
$c_j(\alpha_j-\alpha_1)=0$, $2\le j\le n.$ Thus $c_2=\ldots =c_n=0.$ By $(*)$ we get $f(x)=c_1,$ i.e. $c_1=0,$ a contradiction. The induction step is thus completed. $\blacksquare$
Remark The conclusion does not hold when the nodes are not necessarily positive. For example $ x_1=0$ and $\alpha_k>0.$ If we require all nodes nonzero, take $x_1=-x_2$ and $\alpha_k=2k.$ Then the first two rows of the matrix are equal.
By the intermediate value property it can be proved that the determinant is positive. Indeed,
the function $$F(\alpha_1,\alpha_2,\ldots,\alpha_n)=\det A(\alpha_1,\alpha_2,\ldots,\alpha_n)$$ is continuous.
Consider the function
$$g(t):=F\big((1-t)\alpha_1,(1-t)\alpha_2+t,\ldots,(1-t)\alpha_{n}+t(n-1)\big).$$
$(1-t)\alpha_i+t(i-1), \forall i\in\{1,2,\ldots,n\}$ increases with $i$ thus satisfies the condition for the exponents same as $\alpha_i$ and $i-1$. Then $g(0)=F(\alpha_1,\alpha_2,\ldots,\alpha_n)$ and $$g(1)=F(0,1,\ldots, n-1)=\prod_{1\le i<j\le n}(x_j-x_i)>0.$$
As $g(t)$ is continuous and does not vanish we conclude $g(0)>0.$